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They counteract the inability to initiate movement and catalepsy (muscular rigidity and fixed posture regardless of external stimuli), which in turn results in significantly reduced dopaminergic cell activity that is involved in the direct pathway of movement

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Dulaglutide is a long-acting GLP-1R agonist with a half-life of 4 days (124)

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Data Availability Statement The original contributions presented in the study are included in the article, further inquiries can be directed to the corresponding authors.